Abstract

The psychoactive effects of cannabis, one of the most commonly used narcotics, have been documented extensively. Despite multiple studies being undertaken, there have been only a few longitudinal studies investigating the effect of long term usage of cannabis on various subcortical structures. This study aims at looking deeper into the effects of long term usage of cannabis on different hippocampus subfields1.Participants were split into two groups, cannabis users and healthy controls. All the test subjects filled out the Cannabis Usage and Disorder Identification Test (CUDIT) and underwent T1-structural MRI scans twice, at a baseline and a followup 3 years later. The subfield volumes were measured using the software package Freesurfer with the LongitudinalHippocampalSubfields (v6.0) Module. Lifetime usage in grams was calculated for each participant until baseline and followup, independently, using linear interpolation. Usage of cannabis (lifetime consumption score) was correlated to increased volumes in certain subfields: the CA3 and CA4 in the right hemisphere and the presubiculum in both, the left and right hemispheres at baseline. Other tests including student’s t-test and multivariate analysis of covariance were performed. Tests to understand the effects of varying consumption were also performed. Persistent usage of cannabis, however, did not result in atrophy of the subfields over time. Rather, there were lower growth rates observed in the healthy controls group as compared to that of the cannabis users in certain subfields.

Abstract

As the field of Music Information Retrieval grows, it is important to take into consideration the multi-modality of music and how aspects of musical engagement such as movement and gesture might be taken into account. Bodily movement is universally associated with music and reflective of important individual features related to music preference such as personality, mood, and empathy. Future multimodal MIR systems may benefit from taking these aspects into account. The current study addresses this by identifying individual differences, specifically Big Five personality traits, and scores on the Empathy and Systemizing Quotients (EQ/SQ) from participants' free dance movements. Our model successfully explored the unseen space for personality as well as EQ, SQ, which has not previously been accomplished for the latter. R2 scores for personality, EQ, and SQ were 76.3%, 77.1%, and 86.7% respectively. As a follow-up, we investigated which bodily joints were most important in defining these traits. We discuss how further research may explore how the mapping of these traits to movement patterns can be used to build a more personalized, multi-modal recommendation system, as well as potential therapeutic applications.

Abstract

Musical preferences have been considered a mirror of the self. In this age of Big Data, online music streaming services allow us to capture ecologically valid music listening behavior and provide a rich source of information to identify several user-specific aspects. Studies have shown musical engagement to be an indirect representation of internal states including internalized symptomatology and depression. The current study aims at unearthing patterns and trends in the individuals at risk for depression as it manifests in naturally occurring music listening behavior. Mental well-being scores, musical engagement measures, and listening histories of this http URL users (N= 541) were acquired. Social tags associated with each listener's most popular tracks were analyzed to unearth the mood/emotions and genres associated with the users. Results revealed that social tags prevalent in the users at risk for depression were predominantly related to emotions depicting Sadness associated with genre tags representing neo-psychedelic-, avant garde-, dream-pop. This study will open up avenues for an MIR-based approach to characterizing and predicting risk for depression which can be helpful in early detection and additionally provide bases for designing music recommendations accordingly.

Abstract

Keeping time is fundamental for our everyday existence. Various isochronous activities, such as locomotion, require us to use internal timekeeping. This phenomenon comes into play also in other human pursuits such as dance and music. When listening to music, we spontaneously perceive and predict its beat. The process of beat perception comprises both beat inference and beat maintenance, their relative importance depending on the salience of beat in the music. To study functional connectivity associated with these processes in a naturalistic situation, we used functional magnetic resonance imaging to measure brain responses of participants while they were listening to a piece of music containing strong contrasts in beat salience. Subsequently, we utilized dynamic graph analysis and psychophysiological interactions (PPI) analysis in connection with computational modelling of beat salience to investigate …

Abstract

Recent neuroimaging evidence suggest that there exists a unique individual-specific functional connectivity (FC) pattern consistent across tasks. The objective of our study is to utilize FC patterns to identify an individual using a supervised machine learning approach. To this end, we use two previously published data sets that comprises resting-state and task-based fMRI responses. We use static FC measures as input to a linear classifier to evaluate its performance. We additionally extend this analysis to capture dynamic FC using two approaches: the common sliding window approach and the more recent phase synchrony-based measure. We found that the classification models using dynamic FC patterns as input outperform their static analysis counterpart by a significant margin for both data sets. Furthermore, sliding window-based analysis proved to capture more individual-specific brain connectivity patterns …

Abstract

Music, an integral part of our lives, which is not only a source of entertainment but plays an important role in mental well-being by impacting moods, emotions and other affective states. Music preferences and listening strategies have been shown to be associated with the psychological well-being of listeners including internalized symptomatology and depression. However, till date no studies exist that examine time-varying music consumption, in terms of acoustic content, and its association with users' well-being. In the current study, we aim at unearthing static and dynamic patterns prevalent in active listening behavior of individuals which may be used as indicators of risk for depression. Mental well-being scores and listening histories of 541 this http URL users were examined. Static and dynamic acoustic and emotion-related features were extracted from each user's listening history and correlated with their mental well-being scores. Results revealed that individuals with greater depression risk resort to higher dependency on music with greater repetitiveness in their listening activity. Furthermore, the affinity of depressed individuals towards music that can be perceived as sad was found to be resistant to change over time. This study has large implications for future work in the area of assessing mental illness risk by exploiting digital footprints of users via online music streaming platforms.

Abstract

Keeping time is fundamental for our everyday existence. Various isochronous activities, such as locomotion, require us to use internal timekeeping. This phenomenon comes into play also in other human pursuits such as dance and music. When listening to music, we spontaneously perceive and predict its beat. The process of beat perception comprises both beat inference and beat maintenance, their relative importance depending on the salience of beat in the music. To study functional connectivity associated with these processes in a naturalistic situation, we used functional magnetic resonance imaging to measure brain responses of participants while they were listening to a piece of music containing strong contrasts in beat salience. Subsequently, we utilized dynamic graph analysis and psychophysiological interactions (PPI) analysis in connection with computational modelling of beat salience to investigate how functional connectivity manifests these processes. As the main effect, correlation analyses between the obtained dynamic graph measures and the beat salience measure revealed increased centrality in auditory-motor cortices, cerebellum, and extrastriate visual areas during low beat salience, whereas regions of the default mode- and central executive networks displayed high centrality during high beat salience. PPI analyses revealed partial dissociation of functional networks belonging to this pathway indicating complementary neural mechanisms crucial in beat inference and maintenance, processes pivotal for extracting and predicting temporal regularities in our environment.

Abstract

Musical training causes structural and functional changes in the brain due to its sensory-motor demands, but the modulatory effect of musical training on music feature processing in the brain in a continuous music listening paradigm, has not been investigated thus far. In this work, we investigate the differences between musicians and non-musicians in the encoding of musical features encompassing musical timbre, rhythm and tone. 18 musicians and 18 non-musicians were scanned using fMRI while listening to 3 varied stimuli. Acoustic features corresponding to timbre, rhythm and tone were computationally extracted from the stimuli and correlated with brain responses, followed by t-tests on group level maps to uncover encoding differences between the two groups. The musicians demonstrated greater involvement of limbic and reward regions, and regions possessing adaptations to music processing due to training, indicating greater analytic processing. However, as a group, they did not exhibit large regions of consistent correlation patterns, especially in processing high-level features, due to differences in processing strategies arising out of their varied training. The non-musicians exhibited broader regions of correlations, implying greater similarities in bottom-up sensory processing.

Abstract

Owing to the stigmatization of mental illnesses such as depression in India [1], there is a need for indirect unsuspecting ways to identify risk for depression and provide timely intervention. Healthy-Unhealthy Music scale (HUMS) [2] is one such assessment tool developed on Australian population that uses music engagement as an indicator of anxiety levels and potential high-risk for depression as assessed by Kessler’s Psychological Distress Scale (K10). The current study aims to ascertain its validity in an Indian setting followed by applying machine learning approaches to predict mental well-being from music associations. A diverse group comprising Indian adult population was assessed using HUMS and mental well-being and proneness to depression measures. HUMS structure investigated via Exploratory factor analyses, and concurrent validity tested with correlations to depression risk and wellbeing revealed high external validity and applicability of HUMS in Indian adult population.Furthermore, very low in-sample error for models like Support Vector Machines (SVM) with nonlinear kernels suggests an underlying pattern between HUMS responses and K10 score. Finally, a two-class model resulted in out of sample accuracy of 81%. To conclude, HUMS demonstrates high generalizability and hence applicability in Indian adult population and potential for employing ML models to capture the underlying pattern.

Abstract

The brain is the most complex biological system that exists. Timbre, in its very nature, is a multidimensional concept with several levels of abstraction thus rendering the investigation of its processing in the brain extremely challenging. Timbre processing can be discussed in relation to levels of abstraction. Low- to midlevel representations can be associated with the neural representation of acoustic structure while high-level abstractions correspond to the neural representation of sound source properties. Furthermore, neural correlates of timbre can be broadly classified based on three stimulus categories, that is, those pertaining to music, speech, and environmental sounds. This chapter summarizes studies that have attempted to uncover neural correlates of varying levels of timbre abstractions. Finally, developments in methodological approaches are described, including the shift from univariate to multivariate statistical models, the employment of more naturalistic stimuli, and brain measurement paradigms from hitherto controlled auditory paradigms.