Abstract

Chemical reaction prediction, encompassing forward synthesis and retrosynthesis, stands as a fundamental challenge in organic synthesis. A widely adopted computational approach frames synthesis prediction as a sequence-to-sequence translation task, using the commonly used SMILES representation for molecules. The current evaluation of machine learning methods for retrosynthesis assumes perfect training data, overlooking imperfections in reaction equations in popular datasets, such as missing reactants, products, other physical and practical constraints such as temperature and cost, primarily due to a focus on the target molecule. This limitation leads to an incomplete representation of viable synthetic routes, especially when multiple sets of reactants can yield a given desired product. In response to these shortcomings, this study examines the prevailing evaluation methods and introduces comprehensive metrics designed to address imperfections in the dataset. Our novel metrics not only assess absolute accuracy by comparing predicted outputs with ground truth but also introduce a nuanced evaluation approach. We provide scores for partial correctness and compute adjusted accuracy through graph matching, acknowledging the inherent complexities of retrosynthetic pathways. Additionally, we explore the impact of small molecular augmentations while preserving chemical properties and employ similarity matching to enhance the assessment of prediction quality. We introduce SynFormer, a sequence-to-sequence model tailored for SMILES representation. It incorporates architectural enhancements to the original transformer, effectively tackling the challenges of chemical reaction prediction. SynFormer achieves a Top-1 accuracy of 53.2% on the USPTO-50k dataset, matching the performance of widely accepted models like Chemformer, but with greater efficiency by eliminating the need for pre-training.

Abstract

Automatic detection of prominence at the word and syllable-levels is critical for building computer-assisted language learning systems. It has been shown that prosody embeddings learned by the current state-of-the-art (SOTA) text-to-speech (TTS) systems could generate word- and syllable-level prominence in the synthesized speech as natural as in native speech. To understand the effectiveness of prosody embeddings from TTS for prominence detection under nonnative context, a comparative analysis is conducted on the embeddings extracted from native and non-native speech considering the prominence-related embeddings: duration, energy, and pitch from a SOTA TTS named FastSpeech2. These embeddings are extracted under two conditions considering: 1) only text, 2) both speech and text. For the first condition, the embeddings are extracted directly from the TTS inference mode, whereas for the second condition, we propose to extract from the TTS under training mode. Experiments are conducted on native speech corpus: Tatoeba, and non-native speech corpus: ISLE. For experimentation, word-level prominence locations are manually annotated for both corpora. The highest relative improvement on word & syllable-level prominence detection accuracies with the TTS embeddings are found to be 13.7% & 5.9% and 16.2% & 6.9% compared to those with the heuristic-based features and self-supervised Wav2Vec-2.0 representations, respectively.

Abstract

Vision-language models (VLMs) excel at tasks requiring joint understanding of visual and linguistic information. A particularly promising yet under-explored application for these models lies in answering questions based on various kinds of maps. This study investigates the efficacy of VLMs in answering questions based on choropleth maps, which are widely used for data analysis and representation. To facilitate and encourage research in this area, we introduce a novel map-based question-answering benchmark, consisting of maps from three geographical regions (United States, India, China), each containing around 1000 questions. Our benchmark incorporates 43 diverse question templates, requiring nuanced understanding of relative spatial relationships, intricate map features, and complex reasoning. It also includes maps with discrete and continuous values, covering variations in color mapping, category ordering, and stylistic patterns, enabling a comprehensive analysis. We evaluated the performance of multiple VLMs on this benchmark, highlighting gaps in their abilities, and providing insights for improving such models. Our dataset, along with all necessary code scripts, is available at map-wise.github.io

Abstract

We present EditIQ, a completely automated framework for cinematically editing scenes captured via a stationary, large field-of-view and high-resolution camera. From the static camera feed, EditIQ initially generates multiple virtual feeds, emulating a team of cameramen. These virtual camera shots termed rushes are subsequently assembled using an automated editing algorithm, whose objective is to present the viewer with the most vivid scene content. To understand key scene elements and guide the editing process, we employ a two-pronged approach: (1) a large language model (LLM)-based dialogue understanding module to analyze conversational flow, coupled with (2) visual saliency prediction to identify meaningful scene elements and camera shots therefrom. We then formulate cinematic video editing as an energy minimization problem over shot selection, where cinematic constraints determine shot choices, transitions, and continuity. EditIQ synthesizes an aesthetically and visually compelling representation of the original narrative while maintaining cinematic coherence and a smooth viewing experience. Efficacy of EditIQ against competing baselines is demonstrated via a psychophysical study involving twenty participants on the BBC Old School dataset plus eleven theatre performance videos. Video samples from EditIQ can be found at https://editiq-ave.github.io/.

Abstract

Previous real-time MRI (rtMRI)-based speech synthesis models depend heavily on noisy ground-truth speech. Applying loss directly over ground truth mel-spectrograms entangles speech content with MRI noise, resulting in poor intelligibility. We introduce a novel approach that adapts the multi-modal self-supervised AV-HuBERT model for text prediction from rtMRI and incorporates a new flow-based duration predictor for speaker-specific alignment. The predicted text and durations are then used by a speech decoder to synthesize aligned speech in any novel voice. We conduct thorough experiments on two datasets and demonstrate our method’s generalization ability to unseen speakers. We assess our framework’s performance by masking parts of the rtMRI video to evaluate the impact of different articulators on text prediction. Our method achieves a 15.18% Word Error Rate (WER) on the USC-TIMIT MRI corpus, marking a huge improvement over the current stateof-the-art. Speech samples are available at https://mri2speech. github.io/MRI2Speech/

Abstract

Current Non-Audible Murmur (NAM)-to-speech techniques rely on voice cloning to simulate ground-truth speech from paired whispers. However, the simulated speech often lacks intelligibility and fails to generalize well across different speakers. To address this issue, we focus on learning phoneme-level alignments from paired whispers and text and employ a Textto-Speech (TTS) system to simulate the ground-truth. To reduce dependence on whispers, we learn phoneme alignments directly from NAMs, though the quality is constrained by the available training data. To further mitigate reliance on NAM/whisper data for ground-truth simulation, we propose incorporating the lip modality to infer speech and introduce a novel diffusionbased method that leverages recent advancements in lip-tospeech technology. Additionally, we release the MultiNAM dataset with over 7.96 hours of paired NAM, whisper, video, and text data from two speakers and benchmark all methods on this dataset. Speech samples and the dataset are available at https://diff-nam.github.io/DiffNAM/

Abstract

We study the connection between audio-visual observations and the underlying physics of a mundane yet intriguing everyday activity: pouring liquids. Given only the sound of liquid pouring into a container, our objective is to automatically infer physical properties such as the liquid level, the shape and size of the container, the pouring rate and the time to fill. To this end, we: (i) show in theory that these properties can be determined from the fundamental frequency (pitch); (ii) train a pitch detection model with supervision from simulated data and visual data with a physics-inspired objective; (iii) introduce a new large dataset of real pouring videos for a systematic study; (iv) show that the trained model can indeed infer these physical properties for real data; and finally, (v) we demonstrate strong generalization to various container shapes, other datasets, and in-the-wild YouTube videos. Our work presents a keen understanding of a narrow yet rich problem at the intersection of acoustics, physics, and learning. It opens up applications to enhance multisensory perception in robotic pouring.

Abstract

Image captioning systems are unable to generate fine-grained captions as they are trained on data that is either noisy (alt-text) or generic (human annotations). This is further exacerbated by maximum likelihood training that encourages generation of frequently occurring phrases. Previous works have tried to address this limitation by fine-tuning captioners with a self-retrieval (SR) reward. However, we find that SR fine-tuning has a tendency to reduce caption faithfulness and even hallucinate. In this work, we circumvent this bottleneck by improving the MLE initialization of the captioning system and designing a curriculum for the SR fine-tuning process. To this extent, we present (1) Visual Caption Boosting, a novel framework to instill fine-grainedness in generic image captioning datasets while remaining anchored in human annotations; and (2) BagCurri, a carefully designed training curriculum that more optimally leverages the contrastive nature of the self-retrieval reward. Jointly, they enable the captioner to describe fine-grained aspects in the image while preserving faithfulness to ground-truth captions. Our approach outperforms previous work by +8.9% on SR against 99 random distractors (RD100) (Dessi et al., 2023); and +7.6% on ImageCoDe. Additionally, existing metrics to evaluate captioning systems fail to reward diversity or evaluate a model's fine-grained understanding ability. Our third contribution addresses this by proposing self-retrieval from the lens of evaluation. We introduce TrueMatch, a benchmark comprising bags of highly similar images that uses SR to assess the captioner's ability to capture subtle visual distinctions. We evaluate and compare several state-of-the-art open-source MLLMs on TrueMatch, and find that our SR approach outperforms them all by a significant margin (e.g. +4.8% - 7.1% over Cambrian) while having 1-2 orders of magnitude fewer parameters. We also outperform vanilla SR by +14.4% to +19.5%.

Abstract

This paper introduces ViNet-S, a 36MB model based on the ViNet architecture with a U-Net design, featuring a lightweight decoder that significantly reduces model size and parameters without compromising performance. Additionally, ViNet-A (148MB) incorporates spatio-temporal action localization (STAL) features, differing from traditional video saliency models that use action classification backbones. Our studies show that an ensemble of ViNet-S and ViNet-A, by averaging predicted saliency maps, achieves state-of-the-art performance on three visual-only and six audio-visual saliency datasets, outperforming transformer-based models in both parameter efficiency and real-time performance, with ViNet-S reaching over 1000fps.

Abstract

Automatic detection and severity assessment of dysarthria are crucial for delivering targeted therapeutic interventions to patients. While most existing research focuses primarily on speech modality, this study introduces a novel approach that leverages both speech and text modalities. By employing cross-attention mechanism, our method learns the acoustic and linguistic similarities between speech and text representations. This approach assesses specifically the pronunciation deviations across different severity levels, thereby enhancing the accuracy of dysarthric detection and severity assessment. All the experiments have been performed using UA-Speech dysarthric database. Improved accuracies of 99.53% and 93.20% in detection, and 98.12% and 51.97% for severity assessment have been achieved when speaker-dependent and speaker-independent, unseen and seen words settings are used. These findings suggest that by integrating text information, which provides a reference linguistic knowledge, a more robust framework has been developed for dysarthric detection and assessment, thereby potentially leading to more effective diagnoses.